CRP, an acute-phase serum protein synthesized in response to inflammatory cytokines, produces antitumor effects in animals. CRP174-185 induces the circulation of soluble IL-6 receptor (sIL-6R) and modulates chemotaxis.SEQUENCE: H-Ile-Tyr-Leu-Gly-Gly-Pro-Phe-Ser-Pro-Asn-Val-Leu-OH (trifluoroacetate salt)ONE-LETTER SEQUENCE: IYLGGPFSPNVLMOLECULAR FORMULA: C62H93N13O16MOLECULAR WEIGHT: 1276.5STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: [160369-86-8]SYNONYMS: RESEARCH AREA: CancerREFERENCES:B.P.Barna et al., Cancer Immunol. Immunother., 36, 171 (1993)M.J.Thomassen et al., J. Immunother., 13, 1 (1993)B.P.Barna et al., Cancer Immunol. Immunother., 38, 38 (1994)
SKU(s): CRP-002A, CRP-002B